Pro Tools 11 HD, the premium version, also comes with newly integrated signal metering capabilities for improved quality of your mixes. There are also advanced features for high-definition video editing, allowing you to work with a vast range of formats. PT 11 also supports offline bouncing (up to 16 sources simultaneously) and dynamic plugin processing, which visibly optimizes session performance and lets you export your mixes at the speed of light. You can now pull off large projects without delays and divisions, which gives you greater creative freedom and spares you from unnecessary stress. In practice, this allows you to work with much more virtual instruments and effects at once. In addition, they have optimized the operation of the plugins and applications to enable you to take full advantage of your memory. Pro Tools 11 also came with brand new audio and video engines. It was the first PT upgraded from 32-bit to 64-bit software architecture, making it much more powerful, efficient, and faster than its predecessors. In many regards, Pro Tools 11 was indeed a groundbreaking version of AVID’s audio editing software.
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Although with promises, there are still some challenges, such as complicated procedures and large-scale manufacturing, in terms of clinical translation. Recently, biological membrane-involved nanotechnology has been widely used in fabricating nanoplatforms for drug delivery, immune manipulation, and cancer treatment 9, 10, 11. The natural world provides a host of materials and inspiration for the field of nanomedicine. For instance, photo-based hyperthermia and reactive oxygen species (ROS) have been reported to induce immunogenic cell death for enhanced tumor immunogenicity 7, 8. Cancer nanomedicine, in combination with immunotherapy, offers great potential to amplify antitumor immune responses and sensitize tumors to immunotherapy in a safe and effective manner 6. However, clinical data suggest that only a small fraction (10–30%) of patients respond to the ICB 5. For instance, immune checkpoint blockade (ICB) can be applied to durably eliminate tumors by inhibiting intrinsic down-regulators of immunity, thus boosting the therapeutic efficacy 4. Collectively, the present study demonstrates biological precipitation synthetic strategy of targeted nanoparticles holds great potential for the preparation of microbial membrane-based nanoplatforms to boost antitumor immunity.Ĭancer immunotherapy has been revolutionizing oncology and demonstrating varying degrees of success in certain solid cancers 1, 2, 3. In two tumor-bearing mouse models using female mice, MiBaMc triggered phototherapy synergizes with anti-PDL1 blocking antibody for enhanced tumor inhibition. The released tumor antigens subsequently promote the maturation of dendritic cells in tumor-draining lymph nodes, eliciting T cell-mediated immune response. We find that MiBaMc specifically targets mitochondria and induces amplified photo-damages and immunogenic cell death of tumor cells under light irradiation. We present a mitochondria-targeting nanoplatform, MiBaMc, which consists of Prussian blue decorated bacteria membrane fragments having further modifications with chlorin e6 and triphenylphosphine. Here, electrochemically active Shewanella oneidensis MR-1 can be applied to produce FDA-approved Prussian blue nanoparticles on a large-scale. The marriage of nanotechnology and immunotherapy offers a great opportunity to amplify antitumor immune response in a safe and effective manner. Please ensure that you scroll all the way to the bottom of the folder to retrieve all available files.Cancer immunotherapy is revolutionizing oncology. Before purchasing, please check that you are able to open zip files and ensure that your zip opening software is updated. This is set is also available as part of the EARTH FRIENDLY CLIP ART BUNDLE This set contains all of the images shown. Images in this set include children: carpooling, turning off tap, turning off light, donating clothes, wormery, picking up litter, using energy efficient lightbulb, reusing bags, using wind energy to dry clothes, planting tree, using public transport (bus), cycling, walking, recycling and using/generating solar power.ģ2 images (16 in color and the same 16 in B&W) This is a set of children making an effort to be 'green by caring for their environment and taking steps to preserve it. It combines the classic bubble shooter game with brand new graphics in HD quality and new features such as stats, novice, expert, and master modes. 2Play creates casual games in multiple categories. Bubble Shooter HD 2 is the second sequel to the legendary Bubble Shooter game. Release Date:April 2023 About the Creator:Block Blast is created by 2Play. Mobile: To select and position a shape, place the cursor, press the surface of the touchscreen or trackpad, slide a finger or stylus, and stop pressing the surface. Controls:Mouse: To select and position a shape, place the cursor above the shape, press the left button, slide the mouse, and release the button. Finally, place a shape in one move to create multiple lines. Place the next shape in the best position to partially create a line. You can do this by aiming to group at least three instances of the same-colored bubbles. The stakes are higher in this game, as well as the amount of fun you will have Race against time by trying to get rid of all the bubbles you see on your screen. How to play:Select one of the three polyomino shapes presented initially by the game. Bubbles 2 is the sequel to your favorite bubble-popping classic. If they don't watch an ad, they must attempt to beat their last-best score displayed in gold next to a crown at the top-left corner of the game area. If the player runs out of moves, they can revive their game by watching an advertisement. If the player removes more than one line at a time or single lines in a consecutive fashion, they win extra points for achieving combo moves. Once the bubbles fade away, the player repeats the process to create as many lines as possible until they run out of shapes that fit into the empty cells on the board.īlock Blast rewards the player with points displayed in white above the top center of the board. The game blasts away a completed line and transforms the blocks into square-shaped bubbles that match the color of the last polyomino shape used to complete the line. They complete this task by transferring various polyomino shapes to the board to make rows and columns that feature eight blocks per line. The player's goal is to earn as many points as possible by removing blocks repeatedly from cells on an 8x8 board that features a black, line grid against a dark gray background. Block Blast combines block-puzzle and brick-breaker elements. The media wall is a modular media cabinet fixed with a very large projector screen framed in black. The walls are in white, and the floors are a of a very light cream carpet flooring. The simple light colors used in this media room give this home theater a refreshing and cozy appeal. The speakers are hidden behind the cabinets with fabric door face to let through the sound, and for the screen, a large LCD TV is placed on the media cabinet. The media wall is a simple movable wooden media cabinet in mahogany finish. This is a simple home theater set-up, with olive-painted walls, beige carpet floors and a two-level floor fixed with beige leather lazy boy seats. For the seats, it is fixed with 3-seater plum leather upholstered lazy boys. The media wall is fixed with a simple large projector screen, and the floors is finished with beige carpet with simple diamond patterns. Walls are paneled, with a combination of beige, white moldings and plum. This home theater design combines beige and a deep plum shade for its over-all color scheme. The speakers are attached on the wall but is concealed through a faux column finished with the same black-stained veneers. It has built-in cabinets in which all media-related items are kept. The media wall, however, is veneered with black-stained wood. Most of the space have light-colored finishes: soft white walls, light beige carpet floors, light cream-upholstered L-shape sofa. This home theater design is nice and cozy, perfect for those with limited room space. The floors are fully carpeted in red with embossed patterns in the same color.įor its media wall, no electronic unit is visible aside from the projector screen and low platform, and for the seating, there are two levels and both are furnished with brown velvet-upholstered lazy boy seats. Walls are paneled with light cream base color, gold moldings and red-and-gold pattern wallpaper which matches the detailed coffer ceiling with the same finish/treatment as the walls. This media room/home theater goes an extra mile to give it a more luxurious look. The media wall has a simple projector and a built-in audio unit, and for the seats, there are two levels and both has 3-seater black leather lazy boys. The floor is covered with red carpet with gold diamond patterns adding to the comfort and elegance of the space. This home theater uses a nice shade of marsala paint for both its walls and ceiling, and is framed by white baseboard and cornice. The upper level is the raised platform in which you will find the sofa which can sit 3 or more people, while on the lower level, you will find 2 lounge seats with a black round side table between them. In this view of the home theater, you will see that the room has an upper level and lower level. Wired are concealed behind this raised laminated panel for a nice clean look. The screen/projector wall is emphasized from the rest of the room as its wall is finished with mahogany laminates. The floors are cozy gray carpet with a medium pile, making it comfortable if you intend to sit on the floor. Walls and ceiling are gray, with black baseboard and wall sconces for a dim light when needed. The home theater paint color scheme is dark grays combined with mahogany wood finish which adds a welcome touch of warmth to the space. In the image above the modern home theater design is tastefully designed, with simple modern lines, comfortable furniture and classy finishes. Below is a picture gallery with some amazing home theater systems. The ideal home theater closely resembles the feeling you get in a real movie theater with all of the audiovisual stimulation from the comfort of your own home.Ĭreating the perfect environment for a home theater requires careful planning and design with emphasis on room acoustics, electronic equipment and comfort to achieve the best cinematic experience. These home theater ideas showcase a variety of rooms with large movie screens and high end decor & furnishings. As of Bloons TD 6, the regular bloons consist of: red, blue, green, yellow, pink, black, white, lead, zebra, rainbow, purple, and ceramic bloons. There are three classes of bloons in the game: regular (unnamed in the game), MOAB-class and Boss-class. The bloons always follow the map's set path on the track until they either reach the exit(s), are popped, or are moved to an earlier part of the track by a tower's ability. If a bloon reaches the end of a path, the player loses lives (or in later games, health) once these are all depleted, the game ends. The game is a tower defense game and thus the player can choose various types of towers and traps to place around the track in order to defend against the bloons, gaining 1 in-game dollar for every layer of bloon popped. The main objective of Bloons TD is to prevent Bloons (in-game name for balloons) from reaching the end of a defined track on a map that consists of one or more entrances and exits for the bloons. Money is gained by popping bloons, completing rounds, and collecting bananas from existing banana farms which can be spent on new towers, upgrades for existing ones, or temporary items such as exploding pineapples and road spikes. A handful of towers can stall the bloons and give the other towers more time to pop them by freezing and gluing the bloons. In the game, players attempt to prevent Bloons (the in-game name for balloons) from reaching the end of a set course by placing towers or road items along it that can pop the bloons in a variety of ways, typically by using the power of monkeys. Games in the Bloons series older than Bloons TD 6 are available through the Ninja Kiwi Archive on Steam. Later games in the series expanded to support various mobile platforms, including Android, iOS, Windows Phone, PlayStation Portable, Nintendo DSi, Windows, Linux and MacOS. The game was initially developed as a browser game, built upon the (now unusable) Adobe Flash platform and released in mid 2007. Android, browser (Flash), iOS, macOS, Nintendo DSi, PlayStation Portable, Microsoft Windows, Xbox One, Nintendo Switchīloons Tower Defense (also known as Bloons TD or BTD) is a series of tower defense games under the Bloons series created and produced by Ninja Kiwi. Inside are folders-the Personal folders-named for the people who use this PC. In any case, now you should see the importance of the Users folder in the main hard drive window. But in its little software head, Windows still considers you an account holder and stands ready to accommodate any others who should come along. If you’re the only one who uses this PC, fine-simply ignore the sharing features. Like it or not, Windows considers you one of these people. (You’ll find much more about this feature in Chapter 19.) It’s ideal for any situation where family members, students, or workers share the same PC.Įach person who uses the computer will turn on the machine to find his own separate desktop picture, set of files, web bookmarks, font collection, and preference settings. Why did Microsoft bury my files in a folder three levels deep?īecause Windows has been designed for computer sharing. That’s why your Personal folder can also be installed here.įREQUENTLY ASKED QUESTION: Secrets of the Personal Folder But that’s a lot of burrowing when you just want a view of your empire. Technically, your Personal folder lurks inside the C:→Users folder. This folder bears your name, or whatever account name you typed when you installed Windows.Įveryone with an account on your PC has a Personal folder. As the box below makes clear, Windows keeps all your stuff-your files, folders, email, pictures, music, bookmarks, even settings and preferences-in one handy, central location: your Personal folder. Network opens (what else?) the Network folder, where you can see a map of your home or office network and make changes to the settings. This command opens the HomeGroup window ( HomeGroups). It lets you see what’s on other computers on your home network, so that you can shove folders and files back and forth without running all over the house with a flash drive. HomeGroup is Microsoft’s name for an easy file-sharing system. You’ll find much more on photos and music in Chapter 8. In fact, whatever software came with your phone, digital camera, or MP3 player probably dumps your photos into, and sucks your music files out of, these folders automatically. As you can probably guess, the Music, Pictures, and Videos folders are intended to house them-and these Start menu commands are quick ways to open them. Microsoft assumes (correctly) that most people these days use their home computers for managing digital music, photos, and video collections. Up pops a list of items like File Explorer, Settings, Documents, Downloads, Music, Pictures, Videos, HomeGroup, and Network, so that you can turn on or off the ones you like (bottom). Finally, click “Choose which folders appear on Start” (middle). In the Settings window (top right), choose Personalization. For convenience, let’s call them the left side and the right side.įigure 1-6. You can add other important folders to your Start menu. The Start menu ( Figure 1-4) is split into two columns. Tap to open the Start menu (or to close it!). If you feel that life’s too short, however, tap the key on the keyboard instead, or the button if it’s a tablet. If you’re the type who bills by the hour, you can open the Start menu ( Figure 1-3, lower left) by clicking it with the mouse. But it’s still called the Start menu, and it’s still the gateway to everything on the PC. In Windows 10, as you’ve probably noticed, the word “Start” doesn’t actually appear on the Start menu, as it did for years now the Start menu is just a square button in the lower-left corner of your screen, bearing the Windows logo ( ). Just about everything you do on your PC begins-or can begin-with your Start menu. It lists every useful piece of software on your computer, including commands, programs, and files. That’s why the Start menu is so important ( Figure 1-4). They may as well bear a sticker reading, “No user-serviceable parts inside.” The vast majority of them are not for you they’re support files, there for behind-the-scenes use by Windows and your applications. Windows is composed of 50 million lines of computer code, scattered across your hard drive in thousands of files. Or you could use a wall power supply along with a barrel jack adapter. If you want something that matches the compactness of the Pro Mini, a battery - LiPo, alkaline, coin cell, etc. Pick a power source that suits your project. The Pro Mini doesn't have a barrel jack, or any other obvious way to connect a power supply, so how do you power the thing? The most important factor in any project is what's going to power it. That said, don't let the slower speed scare you away from using the Mini 8MHz is still plenty fast, and the Mini will still be capable of controlling almost any project the Arduino Uno can. We put a slower resonator on the Mini to guarantee safe operation of the ATmega. The Pro Mini 3.3V runs at 8MHz, half the speed of an Arduino Uno. This means that if you've got peripherals that only work at 5V, you might have to do some level shifting before you hook it up to the Pro Mini (or you could go for the 5V variant of the Pro Mini).Īnother major variation from the standard Arduino lies in the speed at which the ATmega328 runs. Unlike the Arduino Uno, which has both a 5V and 3.3V regulator on board, the Mini only has one regulator. The first glaring hardware difference is the voltage that the Mini operates at: 3.3V. The Mini packs almost as much microprocessor-punch as the regular Arduino, but there are a few major hardware changes you should be aware of before you start adapting your project to the Mini. Comparing the size of a standard Arduino Uno with the (aptly named) Pro Mini. Third-party antivirus software could be another reason for Rage 2 not launching. Solution 4: Add the Game to the Exception List of Your Antivirus Disable fullscreen optimizations: If Rage 2 not launching issue appears when you enable fullscreen optimizations, check this option and test the game.Compatibility mode: Check Run this program in compatibility mode for and select a previous version of Windows system.Step 4: If compatibility troubleshooter doesn’t help you fix the problem, you might need to change some compatibility settings manually. This time, select Troubleshoot program and follow the instructions to finish the process. If the problem still exists, you should run the compatibility troubleshooter again. Step 3: In the pop-up window, click Try recommended settings and test the program to check if this helps. Step 2: Under Compatibility tab, click Run compatibility troubleshooter. Then right-click the executable file of Rage 2 and select Properties. Step 1: Press Win I to open File Explorer and navigate to the installation folder of Rage 2. In this case, you need to run compatibility troubleshooter. You could also encounter the mentioned problem because some settings of the game are incompatible with the current Windows operating system. Read More Solution 3: Run Windows Compatibility Troubleshooter for the Game If you are playing the game via Launcher, you should do the same operation to the launcher, and the RAGE 2.exe should be located in C:\Program Files (x86)\ Launcher\RAGE 2 by default. Then you can launch Rage 2 from Steam and check if it works properly. Then set it to run as administrator as step 2 shows. Step 5: Right-click the executable file of Rage 2 and select Properties. Switch to LOCAL FILES tab and click BROWSE LOCAL FILES to navigate to the installation folder of Rage 2. Then right-click Rage 2 from your game list and select Properties. Step 3: Click Apply and OK to save the changes. Step 2: In the pop-up window, click Compatibility tab and check Run this program as an administrator. Step 1: Right-click the shortcut of Steam on desktop and select Properties. If you encounter Rage 2 not launching on Steam, you can: You can try running the game and its launcher as Administrator. Rage 2 not launching or crashing issue could also happen when it lacks administrator privileges. Solution 2: Run the Game as Administrator If Rage 2 won’t launch again, you need to try the next solution. Step 3: In the pop-up window, select Search automatically for updated driver software and then follow the onscreen instructions to finish the process.Īfter installing the latest graphics card driver, you should restart your computer and try launching Rage 2 again. Then right-click your graphics card and select Update driver. Step 2: Double-click Display adapters to expand the category. Step 1: Right-click Start button and select Device Manager. Tip: You can also update the driver via a third-party or download the latest driver from the official website of the manufacturer. You should check it in Device Manager and update your graphics card driver with the latest driver software. You might encounter Rage 2 not launching or crashing when your graphics card driver is outdated or corrupted. Solution 1: Update Your Graphics Card Driver If you don’t find any new game patches or the problem still exists after installing the latest patch, you can try the following solutions. If you are encounter the same issue, the first thing you need to do is to check whether there are available game patches, considering that the developers will keep releasing patches to fix bugs. However, some Windows users report that their Rage 2 won’t launch or the game keeps crashing. As the sequel to Rage which was released in 2011, Rage 2 contracts a huge number of game lovers. It was released for Microsoft Windows, PlayStation 4, and Xbox One on May 14, 2019. Rage 2 is a first-person shooter video game published by Bethesda Softworks.
MAINSTREAM AND BUSINESS CLAMSHELLS. You'll see the most varied mix of touch and non-touch models here. (For more, see our picks for the best budget laptops.) Exception: 2-in-1s, more about which in a moment. In under-$500 machines, a touch screen should be seen as a pleasant surprise, not a given. Let's dig into the major types.īUDGET CLAMSHELLS. Most low-cost machines that are straight-up laptops (that is, models that do not have 2-in-1-type hinges or tablet modes) will not have touch screens, but you'll run across the occasional exception. Which Laptops Have Touch Screens?ĭepending on the specific kind of laptop you're looking at, the tendency toward touch support will vary. Or there might be both touch and non-touch options available at 1080p. When looking at one of these machines, be very much cognizant whether or not the particular screen or screen option you are looking at supports touch.įor example, a laptop might offer a choice of a 1080p (1,920-by-1,080-pixel) touch screen or a 4K (3,840-by-2,160-pixel) display without touch support. This is the case with some mainstream and business-oriented clamshell laptops, especially ones in model lines that sell in lots of subtly different retail configurations, or that have many tweakable configuration options when sold direct. Note that the screens in a given laptop family may come with options for touch and non-touch versions. It's usually seen only in cases where the panel is very large, or uses a display technology that is not available in a variant that can accept capacitive touch (or is cost-prohibitive). More on those later.Ī few panels use an infrared X/Y axis-mapping technology, in which sensors in the bezel cross-reference an interruption of their beams at a specific intersecting screen location, but the employment of this tech in laptops is rare. Note that tap pressure sensitivity is not a parameter that is typically detected through simple finger touch, though certain touch implementations and stylus pens might transmit that. Also detected are parameters such as tap speed, whether you've tapped versus swiped, or if you've executed a multi-finger touch gesture. The capacitive touch layer maps your finger or pen input to coordinates on the screen that determine the position of your touch. (Having to press a little to, say, sign your name on a screen is an earmark of resistive touch.)īack to capacitive, though. When you write or tap on a resistive screen, that upper layer closes a circuit with another layer beneath it. This is in contrast to the resistive touch technology you might see in other implementations of touch screens, in which the upper layer covering the screen flexes. That electrical aspect explains why touch screens don't work if you're wearing gloves. This layer is typically a grid of ultra-fine wires, or a film it needs to be subtle or translucent enough to not interfere with viewability. Most modern laptops make use of what's known as capacitive touch input, in which the over-screen layer detects where you've touched with one or more fingers using the conductivity of your skin. In most cases, a touch-screen-equipped laptop has a conductive digitizing layer, overlaid on the panel element, that allows for tap, pinch, or swipe input. Touch Screens 101: The Basicsįirst of all, some terminology. Below, let's run through the basics of laptop touch screens and why you might (or might not) want one. Based on our in-labs testing and deep-dive reviews, we've compiled above the best touch-equipped machines that have passed through our hands.
Markzware's FlightCheck guides you through the preflight workflow process with a preflight checklist and issues a preflight report with complete print job analysis, highlighting digital print errors, item by item, including incorrect image resolution, missing fonts, incorrect colors, spot colors, transparency and much more. It provides complete quality control of output and helps avoid re-printing jobs, saving printers and publishers valuable time and money.įlightCheck will preflight digital files thoroughly, perform a detailed scan, and warn you about digital print problems, while directing you to them for repair. FlightCheck now supports Adobe CC!įlightCheck by Markzware helps you create excellent output for magazines, catalogs, brochures, advertisements, manuals, and virtually any document intended for print. There are a few other options for single-application preflight for QuarkXPress and InDesign (including FlightCheck Designer, a condensed version of FlightCheck with less customization), but none offer the range of applications that FlightCheck Professional does.ĭisclaimer: The reviewer is an authorized trainer for Markzware FlightCheck (but that just means I think it’s a good product).FLIGHTCHECK is the essential quality control tool for any and all participants in the print and rich media markets, from creative designers to manufacturing professionals and organizations. What you really should ask is, “How much time is lost fixing problems found in PDFs?” or “How much money is lost from jobs not printing properly?” FlightCheck can pay for itself very quickly. Other programs, such as Illustrator and Photoshop, don’t have preflight or collection built-in. You could use a page-layout application’s built-in preflight however, InDesign’s preflight is weak and can’t be customized, and QuarkXPress’ Job Jackets is hard to set up for the average user. Perhaps the major question many will ask is, “Do I need to spend $500 to check my files?” If you’re a printer dealing with strictly PDF files, you could stay with Acrobat to preflight the files, but then it would make sense to have customers run preflight on their files before creating a PDF. Early OS X versions of FlightCheck had some problems, but if you haven’t looked at version 6.01, you should check it out. As with any program, there will still be a few bugs and glitches-but no showstoppers (see the known-issues list under the Updater page). (Note: Acrobat 8 and Illustrator CS3 weren’t listed as supported applications, but both of them ran through FlightCheck without major problems.) The online Help needs to be improved and the PDF manual is out of date. I wish they’d update their support of FrameMaker (stopped at version 6), which is currently at version 7, with 8 on the way, and for newer Microsoft Office files. Users have to switch between native file Ground Control settings and PDF settings-it should be automatic-although this can be automated with the Auto Preflight Detection preferences. In my tests, it did a very good job at finding problems.Ī few things could be improved or updated, however. There have been a few scattered reports of FlightCheck flagging items that weren’t actual errors but I think it’s more an issue of overly aggressive Ground Control settings or not having the latest update. Available options for inspection are too extensive to cover here but a 14-day demo with documentation is available for download. In fact, you could even ask the printer to supply a copy of his or her settings (which can be password-protected). You can customize settings, called Ground Controls, for native files and PDFs, and share them with other users. Plus, it can run the user through the native files to problem areas, fix the file(s), and then collect the job, with all linked graphics and fonts. Where FlightCheck shines is that it can support multiple native applications (including QuarkXPress 7, InDesign CS3, and some Microsoft Office files) and PDF files. It could be as simple as checking to see if a CMYK-only job has any spot colors, or if images have enough resolution for proper output. Preflight takes its name from the aviation industry and is a checklist of inspection points that must meet certain criteria. With design and production continually being pushed into new, less-experienced hands, the need for preflight increases every day. FlightCheck has been around for many years and most prepress workers, if they haven’t used it, are at least familiar with it. |